Least sedating second generation antihistamine Sex chatting script
This sedating activity is sometimes used in managing conditions such as eczema where sleep maybe disturbed due to pruritus.Sedating antihistamines also have significant antimuscarinic activity and should be used with caution in patients with prostatic hypertrophy, urinary retention and angle-closure glaucoma.The affinity for the H1 receptor is 3 and 6 times higher than for cetirizine and fexofenadine, respectively [A literature search of Pub Med/MEDLINE looking specifically at the studies that investigated the effects of increased doses of NSAHs in patients with all subtypes of CU was conducted.For analysis of the efficacy, only double-blind, placebo-controlled studies were selected, whereas uncontrolled studies were excluded.B) According to percentage of symptom-free patients.* Desloratadine 10 mg vs Desloratadine 120 mg, Desloratadine 10 mg vs Levocetirizine 10 mg, Desloratadine 10 mg vs Levocetirizine 20 mg, Desloratadine 20 mg vs Levocetirizine 10 mg, Desloratadine 20 mg vs Levocetirizine 20 mg, Levocetirizine 10 mg vs Levocetirizine 20 mg, Bilastine 40 mg vs Bilastine 80 mg p n.s.
Efficacy of increased doses of nonsedating antihistamines in patients with chronic urticaria. *Fexofenadine 120 mg vs Fexofenadine 240 mg p = 0.01, ¶ Fexofenadine 120 mg vs Rupatadine 20 mg p = 0.0001, ♦ Fexofenadine 240 mg vs Rupatadine 20 mg p = 0.03.
Inducible urticarias include all forms of physical urticarias (cold-induced, heat-induced, solar, and pressure urticaria).
According to the International Guidelines for the management of urticaria and angioedema non-sedating, second generation antihistamines (NSAHs) are recommended for the treatment of CU .
The statistical comparison of the data is shown in Figure .
There were not significant differences in efficacy between fexofenadine and bilastine, rupatadine and bilastine, and desloratadine and levocetirizine.